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Up to 2000x payouts on your picks.

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Play NFL Fantasy Football with PrizePicks

PrizePicks make it simple for anyone to get in on the action for every NFL game, every day. Just pick “More” or “Less” on your favorite players’ stats — like touchdowns or receptions — and watch the game unfold live. Pick between two and six projections to win up to 2000x your money.

Every game is a new opportunity to win big while enjoying the action.

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Pick Any NFL Stats, Any Time

PrizePicks has all the NFL projections you need for your NFL DFS lineup. You can pick from key NFL stats like:

NBA in-app lineup

Latest from the Playbook

Ravens vs. Steelers Spread Pick for Sunday Night Football in Week 18

Get our Ravens vs. Steelers spread prediction for Sunday Night Football in NFL Week 18, plus over/under trends to consider for PrizePicks Team Picks.

Ravens vs. Steelers Prediction, Picks for Sunday Night Football

With the AFC North crown and a playoff spot on the line, let’s make a Ravens vs. Steelers prediction and picks, including projections for RB Derrick Henry.

Lamar Jackson Injury Update: Is Lamar Playing This Week vs. Steelers?

With the Ravens and Steelers set to battle for the AFC North title, let’s dive into a Lamar Jackson injury update and determine whether he will play in Week 18.

Josh Allen Injury Update: Is Josh Allen Playing This Week vs. Jets?

With the Bills and Jets set to do battle on Sunday, let’s dive into a Josh Allen injury update and determine whether he will play in Week 18's season finale.

Lions vs. Bears Prediction, Picks for NFL Week 18: Ben Johnson Revenge Game?

In our Lions vs. Bears prediction and picks, QB Caleb Williams aims to help his head coach pay back QB Jared Goff and his former team for a Week 2 beat down.

Dolphins vs. Patriots Prediction, Picks for NFL Week 18: Stefon Diggs Stays Hot?

Our Dolphins vs. Patriots prediction and picks for NFL Week 18 features PrizePicks player projections for WR Stefon Diggs and PrizePicks Team Picks trends.

Cardinals vs. Rams Prediction, Picks for NFL Week 18: Trey McBride to Star?

Our Cardinals vs. Rams prediction and picks for Week 18 are headlined by QB Jacoby Brissett, TE Trey McBride, and QB Matthew Stafford.

NFL Week 18 Predictions, Best Matchups & Cheat Sheet for PrizePicks

Get the top NFL Week 18 predictions and best matchups in our cheat sheet for PrizePicks, headlined by Texans QB C.J. Stroud.

Saints vs. Falcons Prediction, Picks for NFL Week 18: Bijan and Pitts End Big?

Can Atlanta RB Bijan Robinson and TE Kyle Pitts Sr. end the season on a high? We discuss in our Saints vs. Falcons prediction and picks for NFL Week 18.

Packers vs. Vikings Prediction, Picks for NFL Week 18: Justin Jefferson, More

Our Packers vs. Vikings prediction and picks for NFL Week 18 features PrizePicks player projections for QB J.J. McCarthy and WR Justin Jefferson.

Seahawks vs. 49ers Prediction, Picks for Saturday Night Football

Check out our Seahawks vs. 49ers prediction and picks for Saturday Night Football, including PrizePicks player projections for the Week 18 showdown.

Seahawks vs. 49ers Spread Prediction for Week 18: Can 49ers Pull Off Home Win?

A prime-time Week 18 matchup sees the NFC West title on the line. Let's take a closer look at a Seahawks vs. 49ers spread prediction for Saturday.

Panthers vs. Buccaneers Spread Prediction for Saturday NFC South Title

Get our expert Panthers vs. Buccaneers spread prediction for Saturday NFL Week 18, plus over/under and spread trends for the NFC South title game.

Week 18 NFL Saturday Game Predictions on Spread, Over/Under

For Panthers vs. Bucs and Seahawks vs. 49ers, let’s dive into Week 18 NFL Saturday game predictions on spread and over/unders from PrizePicks Team Picks.

Panthers vs. Buccaneers Prediction, Picks for Saturday: Chris Godwin to Produce?

In a battle for the NFC South title, find our Panthers vs. Buccaneers prediction and picks for Saturday, including PrizePicks projections for WR Chris Godwin.

What NFL Teams Are Resting Starters in Week 18? Packers, Eagles Recharging

With the playoffs in sight, what NFL teams are resting starters in Week 18? Short-handed rotations could impact options on PrizePicks.

NFL Playoff Scenarios & Implications for Week 18 Games

As the 2025 regular season comes to a close, let’s dive into top NFL playoff scenarios and implications for Week 18’s slate as the postseason approaches.

NFL Saturday Games Injury Report: Will George Kittle Play? Who's In and Out?

Let's take a look at the injury report for the NFL Saturday Games, including Panthers vs. Bucs, and if George Kittle is playing in Seahawks vs. 49ers.

Join the NFL Action with PrizePicks Today

The PrizePicks NFL board is always fresh, with daily updates to stat projections, players, and exciting new features like Combo Squares, "Demons and Goblins" game feature, and weekly projection discounts. It’s not just hype — PrizePicks is America’s No. 1 Fantasy Sports app, known for top-tier customer service and the most exciting NFL fantasy experience. That’s why our members keep coming back for more NFL fantasy sports.

What is PrizePicks NFL?

PrizePicks is the simplest and best way to play daily fantasy with real money payouts. Just pick more or less on 2-6 player projections to win up to 2000x your money.

Is PrizePicks NFL real money?

Yes, PrizePicks is a real money fantasy sports game. Cash prizes are applied to your PrizePicks account after your Lineup wins, and you can withdraw funds using a debit card, bank account, or PayPal account.

What is the PrizePicks Promo Code for NFL DFS?

If you’re new to PrizePicks, use promo code NFLPicks to get $50 instantly in lineups after you play your first $5 on PrizePicks.

What is a PrizePicks NFL Lineup?

A PrizePicks Lineup is a combination of at least two player projections — such as points, rebounds, assists, and more. You can pick up to six projections in a Lineup to win up to 2000x your money.

What is the PrizePicks NFL payout rate?

With PrizePicks, you can win up to 2000x your money with one Lineup, depending on the number of picks in your Lineup. You can also choose Power Play — where all picks must be correct — or Flex Play — where you can still cash with one or two incorrect picks.

With Demons and Goblins Projections, you can boost your payout, or play a safer Lineup for lower payout rates,

Learn more here about Payout rates on PrizePicks.

Can I combine NFL picks with other sports?

Yes, PrizePicks allows you to mix-and-match player projections from different sports in one Lineup. You can combine player projections from sports like NFL, NBA, MLB, NHL, CFB, CBB, PGA, esports, and much more!

How much money can I win on PrizePicks NFL?

PrizePicks Lineups payout as high as 2000x! The more player projections you include, the higher the payout!

Power Plays, which require you to predict the correct option on every projection in your Lineup, pay out higher than Flex Plays, which still payout with a loss.

How do I get started with PrizePicks NFL?

Go to the PrizePicks app, sign up, and use code NFLPicks to get $50 instantly in lineups when you play your first $5 Lineup!

Is PrizePicks available in my state?

The PrizePicks Real Money Game is available to residents 18+ in AK, AR, CA, DE, FL, GA, IL, IN,KS, KY, ME, MN, MO, NC, ND, NE, NH, NM, OK, OR, RI, SC, SD, TN, TX, UT, VT, WI, WV, WY, and District of Columbia. 19+ in AL, CO, and Canada (excluding Ontario). 21+ for AZ, MA and VA 

PrizePicks Free to Play (Streak) is available to residents 18+ in CT, MD, MI, MS, NJ, NY, OH, PA. 21+ in IA, LA

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