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PrizePicks make it simple for anyone to get in on the action for every NFL game, every day. Just pick “More” or “Less” on your favorite players’ stats — like touchdowns or receptions — and watch the game unfold live. Pick between two and six projections to win up to 2000x your money.
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Latest from the Playbook
Start ‘Em, Sit ‘Em, NFL Week 17: Welcome to Fantasy Football Championship Week
Can Saints QB Tyler Shough win you a fantasy football championship? We discuss in our Week 17 Start ‘Em, Sit ‘Em — our last Start ‘Em, Sit 'Em of the season.
49ers vs. Colts Spread Prediction for Monday Night Football
On Monday Night Football, find our 49ers vs. Colts spread prediction as Indianapolis tries to snap its four-game losing streak.
49ers vs. Colts Prediction, Picks for Monday Night Football
Find the 49ers vs. Colts prediction for Monday Night Football tonight, including the spread and over/under.
Philip Rivers Stats, Pick: Fortysomething Colts QB Shines on Monday Night Football?
The Indianapolis QB's inspiring journey marches on in our Philip Rivers stats and pick for Monday Night Football.
Christian McCaffrey Stats, Pick: Can 49ers RB Finish 2025 as Fantasy's RB1?
The 49ers star RB looks to keep up his heater on Monday Night Football in our Christian McCaffrey stats and pick.
NFL Week 16 Winners and Losers: Caleb and Darnold Make Magic, Jahmyr Doesn’t
QBs Caleb Williams and Sam Darnold soared, while Jahmir Gibbs made fantasy owners sore, all of which gave us some interesting NFL Week 16 winners and losers.
Top MNF Picks for 49ers vs. Colts on PrizePicks: Purdy-Kittle Connection Shines?
Can QB Brock Purdy and TE George Kittle help lock down a playoff spot for San Francisco? Check out our MNF Picks for 49ers vs. Colts on PrizePicks.
Jonathan Taylor Stats, Pick for MNF: Colts Stud Eyes Rushing Title
Colts RB Jonathan Taylor hasn't hit 100 rushing yards in four straight games.A tough 49rs D could impact our Jonathan Taylor stats and. pick for MNF.
Patriots vs. Ravens Over/Under Pick for Sunday Night Football Tonight
Get the Patriots vs. Ravens prediction for the over/under on Sunday Night Football in NFL Week 16, plus over/under and spread trends for PrizePicks Team Picks.
Patriots vs. Ravens Prediction, Picks for Sunday Night Football: AFC Showdown
Our Patriots vs. Ravens prediction and picks for Sunday Night Football in Week 16 feature New England QB Drake Maye and Baltimore QB Lamar Jackson.
Patriots vs. Ravens SNF Picks for PrizePicks: Trust Drake Maye in Baltimore?
Let's take a look at some Patriots vs. Ravens SNF picks for PrizePicks, including player projections for New England QB Drake Maye and more.
Jaguars vs. Broncos Prediction, 4 p.m. NFL Picks: Broncos Clinch AFC West?
Get the Jaguars vs. Broncos prediction and picks for NFL Week 16, plus over/under, spread, and PrizePicks picks as Broncos look to clinch a playoff schedule.
Drake Maye Stats, Pick vs. Ravens: MVP Hopeful to Shine on SNF?
Can the New England Patriots' MVP hopeful stand out in Week 16? Check out our Drake Maye stats and pick against the Ravens on Sunday Night Football.
TreVeyon Henderson Stats, Pick vs. Ravens for SNF: Key Matchup to Monitor
Check out our TreVeyon Henderson stats, pick, and PrizePicks NFL projections for tonight's Sunday Night Football Patriots matchup against the Baltimore Ravens.
Steelers vs. Lions Prediction, Picks for Week 16: Jahmyr Gibbs to Run Rampant?
For Sunday’s meeting with playoff implications, let’s make a Steelers vs. Lions prediction and picks for Week 16, including projections for RB Jahmyr Gibbs.
Chargers vs. Cowboys Prediction, Picks: Target Justin Herbert, Dak Prescott
Our Chargers vs. Cowboys prediction and picks for NFL Week 16 are headlined by superstar L.A. QB Justin Herbert and Dallas standout Dak Prescott.
NFL Week 16 Predictions, Sunday Cheat Sheet & Expert Picks for PrizePicks
Get the top NFL Week 16 predictions and best matchups to target for PrizePicks picks in Sunday's NFL Cheat Sheet, including Bryce Young and Bijan Robinson.
Buccaneers vs. Panthers Prediction, Picks: Baker Mayfield and Rico Dowdle Crush?
Could we see fireworks from Tampa Bay QB Baker Mayfield and Carolina RB Rico Dowdle? And how might it impact our Buccaneers vs. Panthers prediction and picks?
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