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Up to 2000x payouts on your picks.

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Play NFL Fantasy Football with PrizePicks

PrizePicks make it simple for anyone to get in on the action for every NFL game, every day. Just pick “More” or “Less” on your favorite players’ stats — like touchdowns or receptions — and watch the game unfold live. Pick between two and six projections to win up to 2000x your money.

Every game is a new opportunity to win big while enjoying the action.

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Pick Any NFL Stats, Any Time

PrizePicks has all the NFL projections you need for your NFL DFS lineup. You can pick from key NFL stats like:

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Latest from the Playbook

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Tetairoa McMillan Stats, Pick vs. 49ers: Can Panthers WR Stay on Heater?

With the Panthers rookie WR coming into his own, we dive into Tet McMillan's stats and pick for his Monday Night Football clash with vs. the 49ers.

Kareem Hunt Rocks It, Geno Smith Gets Rocked: NFL Week 12 Winners & Losers

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Brock Purdy Stats, Pick vs. Panthers: Now Healthy, Can 49ers QB Shine on MNF?

The Niners' QB1 is back behind center, so let's break down Brock Purdy's stats and pick for Monday Night Football.

Christian McCaffrey Stats, Pick for MNF vs. Panthers: Can 49ers' RB Stay Hot?

For the first time, the 49ers' RB faces his old team. Check out Christian McCaffrey's stats and pick for Monday Night Football's Week 12 game vs. the Panthers.

Rico Dowdle Stats, Pick vs. 49ers: Big Monday Night For Resurgent RB?

Panthers RB Rico Dowdle is one of the nicer surprises of the 2025 season, so let's check out our take on his stats and pick vs. 49ers for Monday Night Football.

Panthers vs. 49ers Prediction, Picks for MNF: CMC and Mr. Irrelevant, Reunited

49ers QB Brock Purdy is healthy and reunited with RB Christian McCaffrey, so let's check our Panthers vs. 49ers prediction and pick for Monday Night Football.

Bucs vs. Rams SNF Picks Tonight: Chris Godwin, Davante Adams, More

Our Bucs vs. Rams SNF picks for tonight are headlined by Tampa Bay WR Chris Godwin, L.A. WR Davante Adams and QB Matthew Stafford.

Emeka Egbuka Stats, Pick vs. Rams for SNF: Bucs' Rookie WR Takes on L.A.

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Buccaneers vs. Rams Prediction, SNF Picks: Matthew Stafford, NFL MVP?

Top-shelf QBs Matthew Stafford and Baker Mayfield lead our Buccaneers vs. Rams prediction and picks for Sunday Night Football.

Matthew Stafford Stats, Pick vs. Bucs for SNF: Target MVP Hopeful in Prime Time

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Baker Mayfield Stats, Pick vs. Rams for SNF: Bake Show Takes on L.A.

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Puka Nacua Stats, Pick vs. Bucs for SNF: WR to Regain Top Form?

Check out our Puka Nacua stats and pick for Sunday Night Football's Rams vs. Bucs showdown as L.A. attempts to take down Tampa Bay.

Is Bucky Irving Playing vs. Rams on SNF? Week 12 Bucs RB Breakdown

Check out whether Bucky Irving is playing against the Rams on SNF, including PrizePicks projections and stats for the rest of the Buccaneers' RB room.

Falcons vs. Saints Prediction, NFL Week 12 Picks: Kirk Cousins Redemption?

Our Falcons vs. Saints prediction and picks for NFL Week 12 are headlined by QB Kirk Cousins and RBs Bijan Robinson and Alvin Kamara.

Eagles vs. Cowboys Prediction, NFL Picks: Back Saquon Barkley on Sunday

Take a look at some key stats and projections in our Eagles vs. Cowboys prediction for Week 12, including picks for RB Saquon Barkley and WR CeeDee Lamb.

Steelers vs. Bears Prediction, NFL Picks: Can Caleb Williams Keep Winning?

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Jaguars vs. Cardinals Prediction, NFL Week 12 Picks: Eye Trevor Lawrence vs. AZ?

Our Jaguars vs. Cardinals prediction and picks for NFL Week 12 are headlined by QBs Trevor Lawrence and Jacoby Brissett, as well as RB Travis Etienne.

Join the NFL Action with PrizePicks Today

The PrizePicks NFL board is always fresh, with daily updates to stat projections, players, and exciting new features like Combo Squares, "Demons and Goblins" game feature, and weekly projection discounts. It’s not just hype — PrizePicks is America’s No. 1 Fantasy Sports app, known for top-tier customer service and the most exciting NFL fantasy experience. That’s why our members keep coming back for more NFL fantasy sports.

What is PrizePicks NFL?

PrizePicks is the simplest and best way to play daily fantasy with real money payouts. Just pick more or less on 2-6 player projections to win up to 2000x your money.

Is PrizePicks NFL real money?

Yes, PrizePicks is a real money fantasy sports game. Cash prizes are applied to your PrizePicks account after your Lineup wins, and you can withdraw funds using a debit card, bank account, or PayPal account.

What is the PrizePicks Promo Code for NFL DFS?

If you’re new to PrizePicks, use promo code NFLPicks to get $50 instantly in lineups after you play your first $5 on PrizePicks.

What is a PrizePicks NFL Lineup?

A PrizePicks Lineup is a combination of at least two player projections — such as points, rebounds, assists, and more. You can pick up to six projections in a Lineup to win up to 2000x your money.

What is the PrizePicks NFL payout rate?

With PrizePicks, you can win up to 2000x your money with one Lineup, depending on the number of picks in your Lineup. You can also choose Power Play — where all picks must be correct — or Flex Play — where you can still cash with one or two incorrect picks.

With Demons and Goblins Projections, you can boost your payout, or play a safer Lineup for lower payout rates,

Learn more here about Payout rates on PrizePicks.

Can I combine NFL picks with other sports?

Yes, PrizePicks allows you to mix-and-match player projections from different sports in one Lineup. You can combine player projections from sports like NFL, NBA, MLB, NHL, CFB, CBB, PGA, esports, and much more!

How much money can I win on PrizePicks NFL?

PrizePicks Lineups payout as high as 2000x! The more player projections you include, the higher the payout!

Power Plays, which require you to predict the correct option on every projection in your Lineup, pay out higher than Flex Plays, which still payout with a loss.

How do I get started with PrizePicks NFL?

Go to the PrizePicks app, sign up, and use code NFLPicks to get $50 instantly in lineups when you play your first $5 Lineup!

Is PrizePicks available in my state?

The PrizePicks Real Money Game is available to residents 18+ in AK, AR, CA, DE, FL, GA, IL, IN,KS, KY, ME, MN, MO, NC, ND, NE, NH, NM, OK, OR, RI, SC, SD, TN, TX, UT, VT, WI, WV, WY, and District of Columbia. 19+ in AL, CO, and Canada (excluding Ontario). 21+ for AZ, MA and VA 

PrizePicks Free to Play (Streak) is available to residents 18+ in CT, MD, MI, MS, NJ, NY, OH, PA. 21+ in IA, LA

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