CBB DFS Cheat Sheet & Expert NCAA Semifinals Picks - Saturday, 4/5
And then there were four. The NCAA Tournament hits its peak on Saturday as the NCAA Tournament Semifinals roll in San Antonio, Texas, with a pair of monster matchups between the top four college basketball teams in the nation.
We’ve got SEC rivals Florida and Auburn battling at 6:09 p.m. ET on CBS. The second game showcases Duke taking on Houston at 8:49 p.m. ET on CBS. The winners will advance to the National Championship on Monday, with the SEC guaranteed a spot in the championship.
Welcome to the CBB DFS Cheat Sheet, as we break down today’s NCAA tournament Semifinal games and give you the best CBB DFS picks for PrizePicks for Saturday, April 5.
There’s no bigger stage in college basketball than the National Semifinals. The stakes couldn’t be higher.

PrizePicks is the easiest way to cash in on college basketball DFS. Just pick More or Less on player stats across college basketball, lock in your Lineups, and you could turn 6 picks into 1000x!
Let’s dive into the best college basketball picks to target on Saturday in the college basketball semifinals on PrizePicks.
College Basketball DFS Cheat Sheet: National Semifinals
Here’s a look at some of the CBB DFS picks and projections to target in Saturday’s college basketball games for April 5 on PrizePicks.
NCAA Tournament Semifinals Game Previews, Picks
CBB DFS Picks Today for PrizePicks
- Florida F Alex Condon — 17.5 Pts+Rebs
- Auburn G Chad Baker-Mazara — 13.5 Pts+Asts
- Duke G Tyrese Proctor — 15 Pts+Asts
- Houston G Emanuel Sharp — 16.5 Pts+Rebs
NCAA Tournament Semifinals Game Previews, Picks
Here are full previews and analysis for both NCAA Tournament Semifinals on Saturday — Auburn vs. Florida and Houston vs. Duke — including a PrizePicks CBB pick for each game.
Florida vs. Auburn: Preview, Pick
Time: 6:09 p.m. ET
How to Watch: CBS
Florida (34-4) has won 16 of its past 17 games since getting routed at Tennessee on February 1. The Gators got revenge on the Volunteers in the SEC championship, followed by four wins to make the National Semifinals for the first time since 2014.
Along the way, the Gators rallied past two-time defending champion UConn in the second round and erased a late nine-point deficit to stun Texas Tech in the Regional Finals.
Auburn (32-5) lost three of its last four games prior to the NCAA Tournament. Bruce Pearl’s team bounced back to qualify for its first National Semifinals appearance since 2019 after knocking out Michigan State in the Regional Finals.
In the first matchup this season at Auburn, the Gators ousted the Tigers, 90-81, on February 8. Florida shot 58.6% on effective field goal percentage, the highest percentage allowed by Auburn in any game this season.
Here are a few key stats to help you make your DFS picks for Saturday’s Auburn vs. Florida matchup on PrizePicks:
- KenPom projects this game to have an estimated 161 points.
- Auburn F Johni Broome is expected to play without limitation after suffering an arm injury in the second half of Sunday’s win over Michigan State.
- In Broome’s first matchup against Florida, he scored 18 points and pulled down 11 rebounds. His points + rebounds projection at PrizePicks is listed at 29.5 on Saturday.
- Auburn G Miles Kelly led the Tigers with 22 points in the loss to Florida earlier this year.
- Kelly has been limited to 18 points across the last three games, and his points projection on Saturday is 11.5 on PrizePicks.
- Florida G Walter Clayton, Jr. torched Texas Tech for 30 points in the Regional Finals comeback win.
- Clayton, Jr. has knocked down three 3-pointers in three of four tournament games. His 3-point projection against Auburn sits at 2.5 on PrizePicks.
- Florida and Auburn each rank sixth in the country in 3-point defense at 29.6%.
CBB PrizePicks Pick: Florida G Walter Clayton, Jr. — 2.5 3-Pointers
Houston vs. Duke: Preview, Pick
Time: 8:49 p.m. ET
How to Watch: CBS
Duke (35-3) is seeking its first National Championship appearance since 2015, but the Blue Devils need one more win to reach Monday.
Houston (34-4) looks to avenge a Sweet 16 loss to Duke last March, 54-51. The Cougars own the longest current winning streak in the nation at 17, while three of their four losses have come in overtime.
Duke rolled past Alabama in the Regional Finals, limiting the Crimson Tide to eight 3-pointers in a 20-point rout, despite many thinking the Tide could keep it close. 15 of the last 18 wins for Duke have come by 10 points or more — the Blue Devils are dominating opponents.
The Cougars own the top defensive efficiency in the nation and have limited opponents to 44.5% on 2-point shooting, which ranks fifth.
Here are a few key stats to help you make your DFS picks for Saturday’s Houston vs. Duke showdown on PrizePicks:
- KenPom projects this game at 134 total points, far lower than the early game.
- Duke F Cooper Flagg scored 30 points in the round of 16 victory over Arizona.
- Flagg’s points projection against Houston is set at 19 on PrizePicks. He has finished with less than that total in six of the last eight games.
- Duke G Kon Knueppel is fresh off a 21-point effort in the Regional Finals win over Alabama. Knueppel’s points + assists projection is set at 16.5 on PrizePicks.
- The freshman has picked up more than that projection in eight of the last 10 games.
- Houston G L.J. Cryer has scored 16 points or less in three of the last five games. His point projection is 16.5 against Duke, as he scored 15 in the tournament loss to Duke last season.
- Houston’s defense is always touted highly, but the Cougars also rank second in the nation in 3-point shooting at 39.7%.
- Duke and its opponents have scored a combined 135 points in 19 consecutive games.
CBB PrizePicks Pick: Duke G Kon Knueppel — 16.5 Pts+Rebs+Asts
CBB DFS Picks Today for PrizePicks
Here are four CBB DFS picks to use in your PrizePicks CBB Lineups for the college basketball National Semifinals games on Saturday, April 5.
Florida F Alex Condon — 17.5 Pts+Rebs

- Gators F Alex Condon has finished with less than 17 points + rebounds in four consecutive games.
- Condon has been held to single-digit scoring in five of the last seven games.
- Condon scored 17 points and grabbed 10 boards in the first matchup with Auburn this season.
- Since picking up 15 rebounds against Ole Miss on March 8, Condon is averaging 6.3 rebounds in the last seven games.
💰 Use PrizePicks Promo Code "Playbook": Claim free $50 with your first $5+ Lineup
Auburn G Chad Baker-Mazara — 13.5 Pts+Asts

- Tigers G Chad Baker-Mazara has scored nine points or less in six of the last seven games. His points projection on PrizePicks is 11.
- Baker-Mazara’s best game in this stretch came in the second round win over Creighton, scoring 17 points.
- In the last 10 games, Baker-Mazara has dished out more than five assists only three times.
- Baker-Mazara was held to six points and two assists in the loss to Florida earlier this season.
Duke G Tyrese Proctor — 15 Pts+Asts

- Blue Devils G Tyrese Proctor has put together a solid tournament, averaging 17.0 points per game.
- Proctor drilled 13 3-pointers in the first two rounds against Mount St. Mary’s and Baylor.
- Proctor has dished out only seven assists in each of the last three games after a five-assist game against Mount St. Mary’s.
- In last year’s matchup with Houston, Proctor scored nine points and posted four assists.
Houston G Emanuel Sharp — 16.5 Pts+Rebs

- Cougars G Emanuel Sharp scored 16 points in the Regional Finals victory over Tennessee.
- Sharp’s rebounding numbers have gone down during the NCAA Tournament. Sharp averaged 3.0 rebounds a game throughout the season, but the junior has pulled down just seven boards in four tournament victories.
- In last year’s loss to Duke, Sharp was held to seven points and one rebound.
- In four of the past seven games, Sharp has knocked down more than three 3-pointers.

Lock In for the NCAA Tournament Semifinals on PrizePicks
We’ve got two fantastic games in the NCAA Tournament Semifinals on Saturday, as the four No. 1 seeds fight to keep their season alive and move onto the National Championship.
PrizePicks is the best way to get in on the real money NCAA Tournament action for both games and get paid for your college basketball takes. From Cooper Flagg to Johnni Broome, just pick More or Less at least two CBB player stat projections to build your Lineup on PrizePicks.
Use the players above to build your Lineups around, or use a 6-Pick Lineup to reach up to 1000x payouts.
Check out the Playbook for more college basketball picks all the way through the National Championship.