NBA DFS Cheat Sheet & Best NBA PrizePicks for NBA Playoffs Games - 4/21/25

The first set of Game 2s in the NBA Playoffs first round begin tonight on TNT, with the Pistons vs. Knicks and Clippers vs. Nuggets. Below, we’ll give you the top NBA PrizePicks picks for NBA DFS on Monday night in the NBA.

Tonight, the Pistons look to bounce back following a fourth quarter meltdown in Game 1 to the Knicks. Meanwhile, the Nuggets try to capitalize off Saturday’s overtime triumph over the Clippers, in what’s expected to be a tight series. 

PrizePicks is the easiest way to cash in on the NBA Playoffs. Just pick More or Less on player stats across the NBA — from points to rebounds to 3-pointers — and lock in your Lineup.

With Takes 2 Tickets sweepstakes during the NBA Playoffs, your $5 NBA Lineup could win you two courtside tickets at an NBA championship game with all expenses paid by PrizePicks.

Let’s break down some of the best NBA picks to target for the Monday NBA DFS slate on PrizePicks.

NBA DFS Cheat Sheet Today for PrizePicks: April 21

Here are four of the top NBA DFS picks for Monday, April 21, on PrizePicks. Use this analysis to help you make your NBA player picks on PrizePicks. Click each pick to read more.

• Pistons SG Malik Beasley — 15.5 Points
• Knicks SG Mikal Bridges — 22.5 Pts+Rebs+Asts
• Clippers SF Kawhi Leonard — 31.5 Pts+Rebs
• Nuggets SF Michael Porter, Jr. — 14 Pts+Asts

Pistons SG Malik Beasley — 15.5 Points

• Pistons G Malik Beasley scored 20 points in the Game 1 loss to the Knicks, including hitting six 3-pointers.
• Beasley has attempted 10 3-pointers in eight of the last nine games, while knocking down 20 treys in the past three contests.
• Beasley has topped the 20-point mark in three games against New York this season.
• The Knicks closed the regular season ranking 26th in the league in defensive 3-point percentage at 36.7%. The Pistons shot 46.9% from downtown in Game 1.

Knicks SG Mikal Bridges — 22 Pts+Rebs+Asts

• Knicks G Mikal Bridges struggled in Game 1, scoring eight points, pulling down two rebounds, and dishing out a pair of assists.
• The former Villanova standout averaged 19.7 points per game in four regular season meetings with the Pistons.
• Bridges posted 5.6 assists per game in his final 10 regular season contests.
• Bridges grabbed seven rebounds in the first matchup with the Pistons on Nov. 1, but has compiled a total of nine boards in the last four meetings.

Clippers SF Kawhi Leonard — 31.5 Pts+Rebs

• Clippers SF Kawhi Leonard scored 22 points in Saturday’s Game 1 defeat at Denver. 
• Leonard averaged 26.4 points per game in the final 15 regular season contests.
• Since the beginning of March, Leonard has compiled seven rebounds per game, including five double-digit rebound performances. 
• Leonard knocked down at least two 3-pointers in six consecutive games before getting held to one trey in Saturday’s loss.

Nuggets SF Michael Porter, Jr. — 14 Pts+Asts

• Nuggets F Michael Porter, Jr. looks to bounce back from a subpar outing in Game 1. Porter, Jr. was held to three points in 26 minutes, his lowest scoring output of the season. 
• Porter, Jr. averaged 18.0 points per game in the previous three matchups with the Clippers.
• In the past three games, Porter, Jr. has not dished out an assist. Prior to this stretch, he went eight consecutive games with at least two assists. 
• In five games against the Clippers this season, Porter, Jr. is shooting 33% from 3-point range. On the season, he is converting 39.5% of his attempts from long distance.

Win Cash on NBA Playoffs on PrizePicks

With four teams in action on Monday and a busy week of NBA Playoff games, there’s never been a better time to add to the excitement with PrizePicks.

There are plenty of NBA DFS picks to consider for your PrizePicks Lineups tonight, including stars like Jalen Brunson, James Harden, and Nikola Jokic on tonight’s slate.

Just pick More or Less at least two NBA player stat projections to build your Lineup on PrizePicks. Use the players above to build your Lineups around, or build your own, up to 6 picks to win up to 2000x!

Check out the Playbook daily for more NBA DFS picks all the way through the Playoffs.