Saturday NFL Games Cheat Sheet & Best NFL DFS Picks: Divisional Round

One of the best weekends of football is upon us: the 2025 NFL Divisional Round. We’ve got four games on tap, with both No. 1 seeds and Super Bowl favorites taking the field in the two Saturday games.

Below, in the PrizePicks Cheat Sheet for the Divisional Round Saturday games, we’ll give you the best NFL DFS picks on PrizePicks, game predictions, and key stats for the two games featuring the two best teams in the NFL.

The Playbook has given you everything you need to cash out on Divisional Round weekend. Now, it’s time to head to the PrizePicks NFL board and lock in your Lineup. 

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Saturday NFL Game Predictions for Divisional Round

Here are our Divisional Round picks and predictions for the two NFL Saturday games — Texans vs. Chiefs and Commanders vs. Lions, including game predictions, NFL DFS picks, and PrizePicks projections to target.

Winners of each Saturday Divisional Round game will advance to the AFC and NFC Championships next Sunday, January 26, 2025.

🏈 Get Divisional Round predictions for every Playoff game in the PrizePicks Cheat Sheet

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Houston Texans vs. Kansas City Chiefs: Saturday NFL Predictions

Date: Saturday, January 18

Time: 4:30 p.m. ET

Where to Watch: ESPN

✅ Texans vs. Chiefs Expert Player Picks & Game Prediction

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Texans vs. Chiefs Player Picks & Predictions

Here are our staff’s favorite picks for NFL DFS PrizePicks for the Texans vs. Chiefs game on Saturday in the Divisional Round.

• Texans QB C.J. Stroud 243.5 Pass+Rush Yards — More
• Chiefs QB Patrick Mahomes 34.5 Yards Longest Completion — More
• Chiefs WR Xavier Worthy 4.5 Rush Yards — More
• Chiefs WR Xavier Worthy 39.5 Receiving Yards — More (Goblin)
• Texans WR Nico Collins 83.5 Receiving Yards — Less
• Texans TE Dalton Schultz 35.5 Receiving Yards — More

Texans vs. Chiefs: Notable Stats

Get more Texans vs. Chiefs stats for the Divisional Round here.

• The Chiefs went 8-0 at home during the regular season, winning by an average of 5.1 points
• The Texans had 4 INTs vs. Justin Herbert last week. Chiefs QB Patrick Mahomes has not thrown an INT since Week 11.
• Chiefs QB Patrick Mahomes has never lost a Divisional Round game (6-0), throwing for over 300 yards on average, 16 touchdowns, and 0 INTs in those games.
• The Chiefs rank top five in dropback expected points added (EPA) in the two games with Hollywood Brown back — previously ranked 10th.
• This is only the Texans second game this season with their full front seven healthy.
• The Texans defense that ranked 3rd in EPA this year.

AFC Divisional Round Predictions: Chiefs Win

Christian’s Prediction: Chiefs 24, Texans 13

Summary: The healthy Texans defense looked stout in the Wild Card round, but the Chiefs offense looked even better to finish the year. Texans are lacking the weapons to keep up with Patrick Mahomes and Andy Reid’s offense, especially off three weeks rest.

Khadir’s Prediction: Chiefs 34, Texans 14

Summary: This should be an easy game for the Chiefs off extended rest. The Texans have already lost once to the Chiefs, and this is just a mismatch in almost every aspect. Texans flaws and inconsistencies catch up to them, and we could see a blowout to open up the NFL Saturday games.

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Washington Commanders vs. Detroit Lions

Date: Saturday, January 18

Time: 8 p.m. ET

Where to Watch: FOX

✅ Commanders vs. Lions Expert Player Picks & Game Prediction

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Commanders vs. Lions Player Picks & Predictions

Here are our staff’s favorite picks for NFL DFS PrizePicks for the Commanders vs. Lions game on Saturday night in the Divisional Round.

• Commanders QB Jayden Daniels 1.5 Pass TDs — More (Demon)
• Lions WR Amon-Ra St. Brown 77.5 Receiving Yards — Less
• TD Scorer Prediction: Lions RB Jahmyr Gibbs (Goblin)
• Lions WR Jameson Williams 55.5 Receiving Yards — More
• Lions QB Jared Goff 27.15 Pass Yards — More

Commanders vs. Lions: Notable Stats

Get more Commanders vs. Lions stats for the Divisional Round here.

• These teams are top 10 in virtually every offensive metric: points per game, yards per game, rushing yards, third-down conversion rate, score percentage.
• Commanders QB Jayden Daniels has at least 10 carries in seven games this year.
• The Commanders lead the league in no-huddle — 62.4% of Daniels’ snaps were out of no-huddle. He leads the league in pass yards, touchdowns, and first downs out of no-huddle.
• Lions WR Amon-Ra St. Brown has only gone more than his 77.5 receiving yards projection in four games this season, despite averaging 74 yards per game.
• The Lions get back LB Alex Anzalone (who is the defensive playcaller), CB Terrion Arnold, and RB David Montgomery for this game.

AFC Divisional Round Predictions: Lions Win

Christian’s Prediction: Lions 34, Commanders 24

Summary: The Commanders weren’t all that impressive in the win over the Bucs, and looked incredibly vulnerable in pass defense — that’ll be a problem here. The Lions defense has some holes that Commanders QB Jayden Daniels can exploit, but it’s not going to be enough against an incredibly efficient Lions offense that should have its way against a fraudulent Commanders defense that is much worse than it looks on paper.

Austin’s Prediction: Lions 34, Commanders 24

Summary: Expect this game to bring a ton of explosive plays to close out the Saturday games. The Lions’ run game and hard-to-defend passing attack will be a challenge for the Commanders to stop, and the Lions should overwhelm them. Look for the Lions to control possession and out-physical this Commanders defense.

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Win Real Money on NFL Divisional Round Games

The picks are in, now it’s time to lock in and cash out for the NFL Divisional Round on Saturday. The Saturday NFL games feature the top two teams in the NFL. Don’t miss out on the real money NFL action on PrizePicks.

PrizePicks is the easiest way to win real cash with your NFL takes. Pick more or less on player stat projections – like receptions, touchdowns, or passing yards — and get paid if your picks are correct. It’s that simple. The more you pick, the more you could win — up to 1000x your money!

To get analysis on all four NFL Divisional Round weekend games, head to the Divisional Round Cheat Sheet and dig into the top games to target, TD scorer picks, WR vs. CB matchups, and more.