Best MLB Pitcher Picks Today on PrizePicks – 4/22/25
We’re locking in on the best MLB pitcher picks today, as all thirty teams will take the mound in Tuesday night’s games. If you like backing arms over bats, this one is for you.
We’ll highlight the best pitchers and strikeout projections to target on PrizePicks in tonight’s games on Tuesday, April 22, including Dustin May and Chris Bubic’s strikeouts. Find more pitcher, hitters, and a home run picks in today’s MLB DFS Cheat Sheet.
Don’t forget to head to the PrizePicks MLB board, lock in your pitcher picks, and submit your Lineup to get in on the real money MLB action before the first pitch.
Best MLB Pitcher Picks on PrizePicks: Tuesday, 4/22
Here are the top MLB pitcher picks and predictions for PrizePicks today. Use this analysis to build your Lineups on PrizePicks MLB on Tuesday, April 15. Click to read more about each pick.
- Dodgers P Dustin May – 4.5 Strikeouts
- Blue Jays P Chris Bassitt – 17.5 Pitching Outs
- Royals P Kris Bubic – 7.5 Strikeouts
- Phillies P Cristopher Sanchez – 17.5 Pitching Outs
Dodgers P Dustin May – 4.5 Strikeouts
- In his last 65 plate appearances, Dodgers P Dustin May has allowed a 0% barrel rate.
- Over those same 65 plate appearances, he’s yielded a sub‑50% hard‑hit percentage.
- May has also limited hitters to only a 17% fly‑ball rate in that span.
- The Cubs against the right‑handed sweeper in 220+plate appearances, hitters posted a 32% strikeout rate and just a 7% barrel rate.
- May’s advanced metrics include an xERA (expected earned run average) under 2.30 and an xBA (expected batting average) of .202.
Note: Goblin picks reduce your payout on PrizePicks, as they are easier projections to hit.
Blue Jays P Chris Bassitt – 17.5 Pitching Outs (Goblin)
- Over 90+ plate appearances this season, Chris Bassitt has only allowed a 7% barrel rate.
- In those 90+ plate appearances, he conceded a 49% hard‑hit rate and a 24% fly‑ball rate.
- The Astros, in 160+ plate appearances against the sinker, produced a 62% ground‑ball rate and under 10% barrel rate (Bassitts most thrown pitch)
- Bassitt has allowed only one earned run across 18 innings pitched this season.
Royals P Chris Bubic – 7 Strikeouts
- Chris Bubic has recorded a 26.5% strikeout rate in 100+ plate appearances this season.
- Bubic generates a significant swinging‑strike rate of nearly 15%.
- The Rockies have posted a 37% strikeout rate in 150+ plate appearances against lefties.
- Against left‑handed fastballs over 320+ plate appearances since last season, the Rockies have a ugly 31% strikeout rate.
Phillies P Cristopher Sánchez — 17.5 Pitching Outs (Goblin)
- Over his last 100+ plate appearances overall, Sánchez has allowed a 4.5% barrel rate.
- He has conceded a 46% hard‑hit rate in those 100 plate appearances.
- Sánchez has yielded just a 23% fly‑ball rate across that same span.
- The Mets against the left‑handed sinker in 35+ plate appearances, have produced a ugly 42% ground‑ball rate, while also only managing a weak 6% barrel rate.
- In 100 plate appearances versus the Mets overall, Sánchez has recorded a 29% strikeout rate.
- Sanchez has limited Mets hitters to a .220 batting average in those 100+ plate appearances.
Cash in on MLB Picks on PrizePicks
With a loaded Tuesday MLB slate, now is the time to get in on the action on PrizePicks. Just build your MLB Lineup on PrizePicks — whether you’re going with hitters or pitchers — and win real money if your picks are correct.
All you have to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win real money.
Whether you’re going with demons or goblins, there’s always real money MLB action waiting for you on PrizePicks. Stay locked in on the Playbook all season long for MLB player picks every day.
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