Top MLB DFS Picks Today: Best Plays for Thursday 4/24/25
The Thursday MLB slate brings us a short slate before the weekend series begin, highlighted by the Rangers vs. A’s at 10:05 p.m. ET in an AL West matchup.
We’ve got today’s top MLB DFS picks, including pitcher and hitter projections to target on PrizePicks for today’s slate, plus a home run pick.
Whether you’re backing pitchers' earned runs or a hitter’s home run, Thursday MLB slate is stacked with opportunities on PrizePicks. Below, we’ve got four picks to help you build your winning Lineups for Thursday MLB.
Don’t forget to head to the PrizePicks MLB board, lock in your picks, and submit your lineup to get in on the real money MLB action before the first pitch.
MLB DFS Picks on PrizePicks: Thursday, 4/24
Here are the top MLB DFS picks and predictions for PrizePicks today. Use this analysis to build your Lineups on PrizePicks MLB on Thursday, April 24. Click to read more about each pick.
- Giants SS Willy Adames — 0.5 Total Basses (Goblin)
- Rockies OF Brenton Doyle 1.5 Hits+Runs+RBIs (Demon)
- Nationals P MacKenzie Gore — 2.5 Earned Runs (Demon)
- Home Run Pick: Pirates DH Andrew McCutchen
Giants SS Willy Adames — 0.5 Total Bases (Goblin)

- Over the course of more than 300 plate appearances against right-handed hitters last season, Brewers P Tobias Myers allowed batters to barrel the ball at a 9% clip.
- Myers allowed a hard contact rate of 47% and a 26% fly ball rate last year.
- In his most recent plate appearances against right-handed pitching, Adames produced a 30% fly-ball rate, and a 50% hard-hit rate.
Note: Goblin picks decrease your payout on PrizePicks, as they are easier projections to hit.
Rockies OF Brenton Doyle 1.5 Hits+Runs+RBIs (Demon)

- Across his last 40+ plate appearances against right-handed hitters, Royals P Michael Lorenzen endured a whopping 13% barrel rate, allowed hard contact on 60% of batted balls, and saw an elevated 40% fly-ball rate.
- Over the course of his last 45 plate appearances against right-handed arms, Rockies OF Brenton Doyle has 44% fly ball rate on batted balls, a 17% barrel rate, and posted a lofty 58% hard-hit rate.
Nationals P MacKenzie Gore — 2.5 Earned Runs (Demon)

- In his first 120 plate appearances this season, Nationals P MacKenzie Gore has yielded a 12% barrel rate, conceded a 46% fly ball rate, and allowed 37% hard hit rate.
- Gore allowed 10 earned runs over his last four starts, and more than 2.5 earned runs in two of his last four.
- The Orioles rank fourth in the MLB with 19 home runs over the last 14 days, and 11th in wRC+ over that same time frame.
Note: Demon picks increase your payout on PrizePicks, as they are harder projections to hit.
Home Run Pick: Pirates DH Andrew McCutchen

- In Angels P Tyler Anderson's last 85+ plate appearance this season he has allowed a brutal 9% barrel rate, 41% hard-hit rate, and a lofty 46% fly ball rate.
- Anderson throws the 4-seam fastball 46% of the time this season.
- In a small sample of eight plate appearances this season against left-handed fastballs, Andrew McCutchen owns a 40% fly ball rate, 85% hard hit rate, and a 14% barrel rate.
- Dating back to last season in over 50+ plate appearances, McCutchen owns a 40% fly ball rate, 70% hard hit rate and a 20% barrel rate against the lefty fastball.
- McCutchen has a 123 wRC+ and .316 average against left-handed pitchers this year.
Note: Demon picks increase your payout on PrizePicks, as they are harder projections to hit.
Make MLB DFS Picks on PrizePicks
Thursday is the bridge day before the weekend series begin, but there’s plenty of MLB action all day long. There’s no better time to get in on the action.
Just build your MLB Lineup on PrizePicks with your favorite MLB players and win real money if your picks are correct. All you have to do is pick More or Less on at least two player projections — like hits or pitcher strikeouts — to win.
Whether you’re going with demons or goblins, there’s always real money sports action waiting for you on PrizePicks. Stay locked in on the Playbook all season long for MLB player picks every day.